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Boston, MA: American Botanical Council, 1998

A major limitation of this systematic review, and others, is the inability to assess robustly the effect of carnitines on natural conception and pregnancy outcomes as this has not been comprehensively studied to date

Int J Biosci

oral administration of LAC leads to a significant increase in LAC concentrations in both plasma and cerebrospinal fluid (CSF) [33], showing that LAC crosses the bloodbrain barrier and reaches the brain at significant concentrations

The significant positive correlations demonstrated between S1P and L-2HG with CAT and mMRC scores suggest their potential as biomarkers for assessing the risk of acute exacerbations and evaluating symptoms